Script

 ABSTRACT

 

AFRIZAL FADILLAH FAUZI. Antimicrobial Potential of the n-Hexane Fraction of Kesambi Leaves (Schleichera oleosa L.) Against Escherichia coli and Candida albicans (Supervised by Muh. Aris and Firmansyah).

 

      Kesambi (Schleichera oleosa L.) is a tropical forest plant that is spread throughout Indonesia. The use of kesambi has been known for a long time in the field of traditional medicine in treating various kinds of diseases. This study aims to determine the potential inhibition of the n-hexane fraction of Kesambi Leaf against Escherichia coli and Candida albicans which is useful as an antibacterial and antifungal. The research method and data collection were carried out at the Microbiology Laboratory of the Pharmacy Department, Pancasakti University, namely measuring the inhibition area of ​​three concentrations, namely 5 % w/v, 10%, 15%, which included a positive control of ampicillin for antibacterial and ketoconazole for antifungal, as well as a negative control of Na.CMC for both tests. The data obtained were analyzed using the two-way ANOVA method and concluded that the concentrations obtained were the most optimum is shown at a concentration of 15%.

 

Keywords : Kesambi Leaf, Antimicrobial, Escherichia coli, Candida albicans